Omics data analysis can present a significant barrier to research. The myriad of tools and approaches can lead to significant errors in data analysis due to faulty assumptions about the data or a mismatch between the complexity of the software and a user’s knowledge. To address this, ProtiFi has developed SimpliFi™ an online, browser-accessible omics analysis engine that translates data into biological meaning.
SimpliFi™
SimpliFi accepts quantified omics data and allows users of all skill levels to explore and visualize their data in interactive displays of differentially expressed pathways, GO enrichments, cellular markers, protein-protein interaction networks and molecular-level classifications. Simple URLs share web-browser accessible SimpliFi results with end users. Importantly, SimpliFi exclusively uses non-parametric statistics that correctly address both non-Gaussian distributions and the intensity dependence of omics measurements. Results produced from SimpliFi, from fold-changes to p- values, are always presented with confidence intervals to communicate to end-users the potential risks of the next experimental choices. SimpliFi runs on GPUs for rapid analytical times even for large datasets.